The Outcomes of Cytotoxic Admixture Service Unit in Pharmacy Department, Surin Hospital

Abstract

Objective study: To study the outcomes of cytotoxic admixture service unit of Pharmacy department, Surin Hospital
Study Design: Descriptive study(retrospective analysis)
Venue: Cytotoxic admixture service unit, Pharmacy department, Surin Hospital
Method: This retrospective study collected data from 1 October 2002 to 31 March 2003 (6 months). The data comprise of daily cytotoxic preparation record and monthly cytotoxic dispensing report. The data was then analysed by mean of descriptive statistic.
Population: - Daily cytotoxic preparation record
                       - Monthly cytotoxic dispensing report
Result: In the six-month period of the study, 1,351 doses of cytotoxic drugs were prepared and dispensed for 329 patients. From 9 items of cytotoxic medications: 5-Fluorouracil is the most dispensed cytotoxic medication from the unit in volume (732 doses or 54.18% of total preparation). The cytotoxic preparations are mostly from Male Surgery Ward (248 cases or 37.63% of total cytotoxic preparation). The study also determine the satisfaction of invole staff to cytotoxic unit service. The servey, which run by questionnaire, indicate that they satisfied with this service due to diminishing risk of cytotoxic exposure on patient ward. In economic espect, the cytotoxic unit saved the expense of cytotoxic medication, which cost 9,650.020 baht during period of study.
Conclusion: According to the study, the outcome of cytotoxic unit activities were considered in the quantities of prepared products include any saving cost from such a central cytotoxic unit model. Though the saving value is very little when compare to the cost of investment. However, the important benefit of the unit is to reduce risk of cytotoxic exposure caused by preparation and administration on patient. Regardless of economic aspect, occupational health status improved and the involed staffs therefore satisfied with the service. In addition, the cytotoxic unit activities also provide the pharmaceutical care to cancer patient. Aiming to enhance the quality of treatment and patient’s life.