Neonatal hyperbilirubinemia in Nangrong Hospital Buriram Province

Abstract

Objective: To explore causes of neonatal hyperbilirubinemia and to compare their severities at Nangrong hospital. Buriram province.
Setting: Nangrong hospital.
Study design: Retrospective descriptive study
Subject: 182 new born infants, gestational age of 37 weeks and over, who were diagnosed hyperbilirubinemia and admitted in Nangrong hospital during August 1st 2006 - July 31th 2007 were included in this study.
Method: All new born infants gestational age of 37 weeks and over, who were diagnosed hyperbilirubinemia and admitted in Nangrong hospital during August 1st 2006 - July 31th 2007 were assessed for the causes of neonatal hyperbilirubinemia and compare their severities (onset of jaundice, maximum MB, number of phototherapy day)
Results: 182 infants were diagnosed hyperbilirubinemia and received phototherapy. 88 cases had no definite cause (Inconclusive jaundice), 60 cases-G6PD deficiency, 9 cases-Breast feeding jaundice, 6 cases- Breast milk jaundice, 5 cases-Infection, 4 cases-Cephalhematoma, 3 cases-Other factors contributing jaundice, 1 cases-Polycythemia, 1 case-Hypothyroid with Down syndrome, 5 cases that had 2 causes. Jaundice from G6PD deficiency with ABO incompatibility and G6PD deficiency with Hypothyroid with Down syndrome were detected earlier, jaundice from G6PD deficiency with sepsis had the highest maximum MB, G6PD deficiency with ABO incompatibility received the longest days of phototherapy, 66 case were readmitted (36.26% of all cases, 26.37% born at Nangrong hospital and 1.75% of full term live-births that born at Nangrong hospital) 1 readmitted infant received re-phototherapy (0.55%). The most re-hospitalization causes were inconclusive jaundice and G6PD deficiency.
Conclusions: We should measure bilirubin level and G6PD level in all of newborn infants for early detection and close follow up if the report has abnormal value.
Key word: Neonatal hyperbilirubinemia.