Diagnostic Value of Ultrasound in Patients Suspected Acute Appendicitis
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Abstract
Background: Acute appendicitis is a common surgical problem worldwide. Radiologic investigations haveroles in the patient with equivocal sign and symptoms for acute appendicitis to suggest the likely diagnosis and to exclude other causes of abdominal pain, causing proper management and less complication. Nowadays, ultrasound has increased roles as diagnostic tool to evaluate patientssuspected acute appendicitis due to no radiation exposure and cheaper than CT.
Objective: To evaluate the diagnostic accuracy of ultrasound in patients with suspected acute appendicitis and right lower quadrant pain.
Methods: This diagnostic accuracy researchis retrospective cross-sectional design with population-based data collection. Ninety-nine patients with right lower quadrant pain were investigated with ultrasonography to rule out acute appendicitis during 1st. August 2020 and 24th. February 2021. The findings from ultrasonography were reviewedwhether the appendix was visualized or not and also recorded other findings. Then the results were compared to pathological diagnosis for patients who underwent surgery and review the clinical record before discharge or follow-up record in non-operative patients.
Results: Diagnostic performance of the ultrasound in diagnosis acute appendicitis in this study shows sensitivity 50%(95% CI;31.3-68.7), specificity 95.7% (95% CI;87.8-99.1)positive predictive value83.3%(95% CI; 58.6-96.4) and negative predictive value81.5% (95% CI; 71.3-89.2). The appendix was not visualized in 76.8% of the examinations,visualized appendix size > 6 mm. 18.2%, echogenic peritoneal fat 3%, free fluid 12.1% and fluid collection 6.1%
Conclusion: Ultrasound shows low sensitivity but high specificity for acute appendicitis. Therefore,ultrasound could be used as the first imaging test. But if the appendix is not visualized but clinically suspected acute appendicitis, correlation with clinical context or further CT is considered.
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References
Ferris M, Quan S, Kaplan BS, Molodecky N, Ball CG, Chernoff GW, et al. The Global Incidence of Appendicitis: A Systematic Review of Population-based Studies. Ann Surg 2017;266(2):237-41. doi: 10.1097/SLA.0000000000002188.
Rybkin AV, Thoeni RF. Current concepts in imaging of appendicitis. Radiol Clin North Am 2007;45(3):411-22, vii. doi: 10.1016/j.rcl.2007.04.003.
Espejo OdJA, Mejía MEM, Guerrero LHU. Acute appendicitis: imaging findings and current Approach to diagnostic images. Rev Colomb Radiol 2014; 25(1): 3877-88.
Expert Panel on Gastrointestinal Imaging:, Garcia EM, Camacho MA, Karolyi DR, Kim DH, Cash BD, et al. ACR Appropriateness Criteria ® Right Lower Quadrant Pain-Suspected Appendicitis. J Am Coll Radiol 2018;15(11S):S373-S387. doi: 10.1016/j.jacr.2018.09.033.
Costello JE, Cecava ND, Tucker JE, Bau JL. CT radiation dose: current controversies and dose reduction strategies. AJR Am J Roentgenol 2013;201(6):1283-90. doi: 10.2214/AJR.12.9720.
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009;42(2):377-81. doi: 10.1016/j.jbi.2008.08.010.
Puylaert JB. Acute appendicitis: US evaluation using graded compression. Radiology. 1986 Feb;158(2):355-60. doi: 10.1148/radiology.158.2.2934762.
D'Souza N, D'Souza C, Grant D, Royston E, Farouk M. The value of ultrasonography in the diagnosis of appendicitis. Int J Surg. 2015 Jan;13:165-169. doi: 10.1016/j.ijsu.2014.11.039.
Pacharn P, Ying J, Linam LE, Brody AS, Babcock DS. Sonography in the evaluation of acute appendicitis: are negative sonographic findings good enough?. J Ultrasound Med 2010;29(12):1749-55. doi: 10.7863/jum.2010.29.12.1749.
Prapruttam D, Klawandee S, Tangkittithaworn P, Wongwaisayawan S. Effect of alvarado score on the negative predictive value of nondiagnostic ultrasound for acute appendicitis. [Internet]. 2021. 2001 [cited 2022 Feb 25]; Available from:URL: https://www.jmuonline.org/temp/JMedUltrasound000-2451871_064838.pdf.
Cohen B, Bowling J, Midulla P, Shlasko E, Lester N, Rosenberg H, et al. The non-diagnostic ultrasound in appendicitis: is a non-visualized appendix the same as a negative study?. J Pediatr Surg 2015;50(6):923-7. doi: 10.1016/j.jpedsurg.2015.03.012.
Daga S, Kachewar S, Lakhkar D, Jethlia K, Itai A. Sonographic evaluation of acute appendicitis and its complications. West Afr J Radiol 2017;24(2):152-6. DOI: 10.4103/wajr.wajr_41_16
Hosseini A, Omidian J, Nazarzadeh R. Investigating Diagnostic Value of Ultrasonography in Acute Appendicitis. Adv Biomed Res 2018;7:113. doi: 10.4103/abr.abr_79_18.
Pedram A, Asadian F, Roshan N. Diagnostic Accuracy of Abdominal Ultrasonography in Pediatric Acute Appendicitis. Bull Emerg Trauma 2019;7(3):278-83. doi: 10.29252/beat-0703011.
Al-Ajerami Y. Sensitivity and specificity of ultrasound in the diagnosis of acute appendicitis. East Mediterr Health J 2012;18(1):66-9. doi: 10.26719/2012.18.1.66.
Chakraborty AK, Olcott EW, Jeffrey BR. Hyperechoic Abdominal Fat: A Sentinel Sign of Inflammation. Ultrasound Q 2019;35(2):186-94. doi: 10.1097/RUQ.0000000000000387.
Partain KN, Patel A, Travers C, McCracken CE, Loewen J, Braithwaite K, et al. Secondary signs may improve the diagnostic accuracy of equivocal ultrasounds for suspected appendicitis in children.
J Pediatr Surg 2016;51(10):1655-60. doi: 10.1016/j.jpedsurg.2016.03.005.