Incident of Colon Cancer among Patient Undergoing Colonoscopy Screening in Satuek District Node, Buri Ram, Thailand

Abstract

Background: Colon cancer is the most common of cancer registry in Thailand 2564, originating from polyps that increase in size and undergo metaplasia. Colonoscopy for screening and prompt polypectomy are crucial for the early diagnosis of colon cancer in its initial stages.
Objective: 1) To study the incidence of colon cancer among individuals undergoing colonoscopy screening in the health service network area of Satuek District, Buri Ram Province from 2018 to 2022 2) To compare the incidence of colon cancer among individuals undergoing colonoscopy screening, categorized by health service network area, in Satuek District, Buri Ram Province, from 2018 to 2022.
Methods: This is a retrospective research study. (Retrospective study) by conducting a retrospective study of data from a registry database of people who came to undergo endoscopy screening in the health service network area of Satuek District, Buri Ram Province, including Satuek Hospital, Phutthaisong Hospital, Ban Mai Chai Phot Hospital, Khaen Dong Hospital, Ban Dan Hospital, and Khu Mueang Hospital Analyze incidence data over a 5-year period from 2018 – 2022. The sample group used in the research was people who came to receive endoscopy screening at the health service network area. Analysis of incidence data by spss, STATA, R. and analyze the trend and size of change in incidence rates (Average annual percent change) by means of joinpoint regression analysis, test the model by means of Monte Carlo Permutation.
Results: The result of this study found that male colon cancer incidence is higher than incidence of female colon cancer. Males (55.5%) had an incidence rate of 40.8 per 100,000 people and females (44.5%) had an incidence rate of 30.3 per 100,000 people, which factors In terms of gender, it was also found to be related to the incidence of colon cancer among those who came for colonoscopy screening in the health service network area of Satuek District, Buri Ram Province. This issue has also been further explained. Colon cancer is associated with the ABCB11 gene, which is approximately 2 times more expressed in males than in females. Age is one of importance risk factors which increase chance of colon cancer. People aged 60 years and over have a higher percentage of disease than people aged 15 - 59 years. which the age factor It is considered one of the important personal risk factors that increase the chance of developing colon cancer. A history of smoking is significantly associated with the development of colon cancer. Most of the sample gave a history of not smoking. Therefore, it may depend on the context of the area. For example, 12 percent of colon cancer patients who smoke die and long-term smoking is associated with the growth of adenomatous polyp.
Conclusion: Factor that related with the incidence of colon cancer among individuals undergoing colonoscopy screening in the health service network area of Satuek District, Buri Ram province namely gender (p-value = 0.038), age (p-value = 0.022), and a history of smoking (p-value = 0.005).