A Randomized Clinical Trial Comparing Intra articular Injection of Triamcinolone to Ketorolac in Chronic Rotator Cuff Tendinosis
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Abstract
Background: Chronic rotator cuff tendinosis is a major cause of shoulder pain and dysfunction. However, the effectiveness of treatment options such as intra-articular corticosteroid injections versus non-steroidal anti-inflammatory drugs is still controversy.
Objective: This study aims to evaluate the efficacy of intra-articular injections of triamcinolone compared to ketorolac in chronic rotator cuff tendinosis among patients.
Methods: A randomized clinical trial design was employed, enrolling individuals diagnosed with chronic rotator cuff tendinosis between January 2022 and January 2024. A sample of 40 participants were randomly assigned to receive a single intra-articular injection of either triamcinolone or ketorolac. The efficacy of these interventions was assessed by changes in the Constant score (CS) and ASES score at 1 week, 1 month, and 3 months post-injection. Independent t-tests were utilized to compare the outcomes between the two groups.
Results: At 1 week post-injection, the ASES score of the triamcinolone injection group was significantly higher than that of the ketorolac injection group (Triamcinolone: 80.7 ± 16.0 Ketorolac: 70.0 ± 16.1, p=0.04). At 1 and 3 months post-injection, no significantly different between CS and ASES score (1 month pcs= 0.68, pASES=0.88 3 month pcs= 0.23, pASES=0.37).
Conclusions: Intra-articular injections of both triamcinolone and ketorolac offer benefits in managing chronic rotator cuff tendinosis, with triamcinolone demonstrating a slight advantage in terms of rapid symptom improvement. However, the choice between triamcinolone and ketorolac should be individualized. Future research should encompass larger, more diverse populations and incorporate MRI assessments.
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