Complication of Sinusitis in Hospitalized Patients : Factors Associated with Clinical Outcomes
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Abstract
Background: Paranasal sinusitis is widespread and can cause complications which can leads to fatal and morbidity.
Objective: To determine the complications of sinusitis in hospitalized patients and investigate factors that associated with clinical outcomes.
Patients and Methods: A retrospective study was performed on patients with sinusitis who were admitted in Buriram hospital from 2012 to 2023. After exclude patients with history of tumor and post radiation or surgery in paranasal area, the data were reviewed.
Results: Sixty-five patients were included in the study, which 26 had complication (40.0 %). The most common complication was Orbital complication ( 50.0 % of all complication ) , Intracranial complication (6.2%), Local complication (10.8%) and Isolate cranial nerve palsy (4.6% ). There are 6 patients (9.2%) had multiple complications. Patient with diabetes mellitus were significantly associated with complication and prolong length of stay (p < 0.05). After 3 months of treatment, 18 of complication group have good outcome ( Full recovery (65.4%) and improved outcome (3.8%)).Another 30.8% had poor outcome (8 case),which were blindness (3 case) , visual impairment (1 case), oroantral fistula (1 case) and death (3 case). Patient with intracranial complication and fungal infection were significantly associated with poor outcome ( p < 0.05) . Patient who undergo endoscopic sinus surgery within 72 hours have significantly better outcome ( p <0.05).
Conclusion: Severe complication of sinusitis can cause morbidity and death among patients. Patient with diabetes mellitus were significantly associated with complication and prolonged length of stays. Eventhough most common complication of rhinosinusitis was orbital complication but outcomes of the treatment depend on type of complications and pathogen, which the poor outcome were associated with intracranial complication and fungal infection. Early performed Endoscopic sinus surgery in patients with complication significantly associated with good outcome of treatment.
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