Impact of Diabetes, Obesity or excessive weight gain on birthweight and pregnancy outcomes, retrospective study in BMA General hospital

Main Article Content

ฐิติกัญ ปรีชาพานิช

Abstract


Objective: To study the association between diabetic with or without excessive weight gain and


birthweight.




Method: Retrospective study of 577 pregnant women who labourat BMA general hospital and between


18-35 years old were divided to 4 groups; normal weight gains pregnancy group, obesity or excessive weight


gain pregnancy group, gestational diabetes mellitus (GDM) group and both conditions in pregnancy group.




Result: Five hundred and seventy-seven pregnancies were enrolled. Maternal age, BMI, excessive


weight gain in 4 groups were difference significantly. Average birth weight in each groups were 3,027 3,274


3,210 3,438 grams respectively, were difference significantly (p<0.01). Use logistic regression revealed


that excessive weight gain group had 5 times increase risk to have macrosomia compare with normal weight


gain pregnancy group. DM group was significantly associated with increased risk to occur birth asphyxia,


hypertension and cesarean section (p<0.01). Postpartum hemorrhage was no difference between 4 groups.




Conclusion: The significant risk factor associated with macrosomia was excessive weight during pregnancy.


GDM was associated with birth asphyxia, hypertension and cesarean section.



Key word: Gestational diabetes mellitus, fetal macrosomia, excessive weight gain.

Article Details

How to Cite
ปรีชาพานิช ฐ. (2019). Impact of Diabetes, Obesity or excessive weight gain on birthweight and pregnancy outcomes, retrospective study in BMA General hospital. Journal of Charoenkrung Pracharak Hospital, 12(1), 12–22. retrieved from https://he02.tci-thaijo.org/index.php/JCP/article/view/177385
Section
Original Article

References

1. Rajesh Rajput, Yogesh Yadav, Smiti Nanda. Prevalence of gestational diabetes & associate risk factors at a tertiary care hospital in Haryana.
India J med Res 2013; 137: 728-733.

2. ธีระ ทองสง. โรคเบาหวานในสตรีตั้งครรภ์.ใน:ธีระ ทองสง,สุชยา ลือวรรณ, บรรณาธิการ. สูติศาสตร์ เรียบเรียง. พิมพ์ครั้งที่ 5.
ปทุมธานี: PB FORBOOK xm6,Tkou. sohk 425-38.

3. Triunfo S, Lanzone A. Impact of overweight and
obesity on obstetric outcomes. Journal of
Endocrinological investigation 2014; 37: 323-9.

4. Lao TT1, Wong KY. Perinatal outcome in large-
for-gestational-age infants. Is it influenced by
gestational impaired glucose tolerance?. J Reprod
Med 2002; 47: 497-502.

5. Casay BM, Lucas MJ. Pregnancy outcomes in
women with gestational diabetes compared with
the general obstetric population. Obstet Gynecol
1997; 90: 869-73.

6. Jensen MD. Obesity. In: Goldman L, Schafer
th
AI, editors. Goldmanûs Cecil Medicine. 24 ed.
Philadelphia, PA: Saunders Elsevier 2011; chap
227.

7. American College of Obstetricians and
Gynecologists. Committee Opinion No.549:
Obesity in pregnancy. Obstet Gynecol 2013; 121:
213-7.

8. Lashen H, Fear K, Sturdee DW. Obesity is
associated with increased risk of first trimester
and recurrent miscarriage: matched case-control
study. Hum Reprod 2004; 19: 1644-6.

9. Baeten JM, Bukusi EA, Lambe M. Pregnancy
complications and outcomes among overweight
and obese nulliparous women. Am J Public Health
2001; 91: 436-40.

10. Cedergren MI. Maternal morbid obesity and the
risk of adverse pregnancy outcome. Obstet
Gynecol. 2004; 103: 219-24.†

11. Cnattingius S, Bergstrom R, Lipworth L, Kramer
MS. Prepregnancy weight and the risk of adverse
pregnancy outcomes. N Engl J Med 1998; 338:
147-52.†

12. Oken E, Taveras EM, Kleinman KP, Rich-Edwards
JW, Gillman MW. Gestational weight gain and
child adiposity at age 3 years. Am J Obstet
Gynecol 2007; 196: 322.e1-8.

13. American College of Obstetricians and
Gynecologists. Fetal macrosomia. ACOG Practice
Bulletin 22. Washington, DC: ACOG; 2000.

14. American College of Obstetricians and
Gynecologists. Committee Opinion No.548:
Weight gain during pregnancy. Obstet Gynecol
2013; 121: 210-2.

15. Crane JM, White J, Murphy P. The effect of
gestational weight gain by body mass index on
maternal and neonatal outcomes. J Obstet
Gynaecol Can 2009; 31: 28-35.

16. Marin J.A., Russu M., Hudita D, Nastasia S.
Diabetes, Obesity and Excessive weight gain and
Pregnancy outcomes. Timisoara Medical Journal
2009; 59: 184-7.

17. Chow S, Shao J, Wang H. Sample Size
Calculations in Clinical Research. 2nd ed.
Chapman & Hall/CRC Biostatistics Series 2008;
p.100.