The elderly and long-term effects of COVID-19 pandemic era
Main Article Content
Abstract
Introduction: In the past 2-3 years, a world met with a pandemic of SARS-COV-2 or “COVID-19”. This infection changes many things, not just physical organ but also mental and socioeconomic. Nowadays, Thailand is entering aging society. Therefore, long-term effects of COVID-19 pandemic in elderly need to know for treatment and prevention.
Objective: To summarize and present the long-term effects of COVID-19 infection in older people in terms of physical, mental and social aspect.
Method of study: To investigate the updated evidence published in the qualified and acceptable both Thai and international review journal. Then, present the relevant information in each section.
Results: The COVID-19 infected elderly patients have high morbidity and mortality rates. Especially in
octogenarian, the mortality outcome is as high as 20%. Nowadays, Thailand has entered a fully-aged society
where the population of > 65 years old is more than 20%. Health care professionals should know about the
long-term complications of the COVID-19 infection, called “Long COVID-19 Syndrome”. Not just that, they
need to know about hidden problems are often occurred in the older people such as delirium, mild cognitive
disorder, dementia and post-traumatic stress disorder. In terms of social impact, older people are not directly
affected, but they are indirectly affected by children losing their jobs or changing jobs due to lockdown,
causing a financial recession.
Conclusion: The COVID-19 outbreak effects not only the general public. But it effects older people in many
aspects, including physical, intellectual, mental and social, which is something that should be realized and
prevented from causing problems that cause disability or increasing mortality outcome. All these problems
need to early detection, prevention and treat for improving quality of life of the elderly.
Article Details

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References
Tosato M, Carfì A, Martis I, Pais C, Ciciarello F, Rota E, et al. Prevalence and predictors of persistence of COVID-19 symptoms in older adults: a single-center study. J Am Med Dir Assoc 2021;22(9):1840-4.
Recinella G, Marasco G, Battista AD, Bianchi G, Zoli M. Prognostic role of nutritional status in elderly patients hospitalized for COVID-19: a monocentric study. Aging Clin Exp Res 2020; 32(12):2695-701.
กองทุนสนับสนุนสร้างเสริมสุขภาพ(สสส.). การเผชิญหน้า-‘สังคมผู้สูงอายุ’-โจทย์ท้าทายภาระค่าใช้จ่ายที่เพิ่มขึ้น [อินเทอร์เน็ต]. 2565 [เข้าถึงเมื่อ 6 มิ.ย. 2566]. เข้าถึงได้จาก: https://resourcecenter.thaihealth.or.th/article/
Guo J, Wei X, Li Q, Li L, Yang Z, Shi Y, et al. Single‐cell RNA analysis on ACE2 expression provides insights into SARS‐CoV‐2 potential entry into the bloodstream and heart injury. J Cell Physiol 2020; 235(12):9884-94.
Dayaramani C, D Leon J, Reiss AB. Cardiovascular disease complicating COVID-19 in the elderly. Medicina 2021;57(8):833.
Puntmann VO, Carerj ML, Wieters I, Fahim M, Arendt C, Hoffmann J, et al. Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from coronavirus disease 2019 (COVID-19). JAMA cardiol 2020;5(11):1265-73.
Kalra RS, Dhanjal JK, Meena AS, Kalel VC, Dahiya S, Singh B, et al. COVID-19, neuropathology, and aging: SARS-CoV-2 neurological infection, mechanism, and associated complications. Front Aging Neurosci 2021;13:662786.
Yang K, Wen G, Wang J, Zhou S, Da W, Meng Y, et al. Complication and sequelae of COVID-19: what should we pay attention to in the post-epidemic era. Front Immunol 2021;12:711741.
Fung KW, Baye F, Baik SH, Zheng Z, McDonald CJ. Prevalence and characteristics of long COVID in elderly patients: an observational cohort study of over 2 million adults in the US. PLoS Med 2023;20(4): e1004194.
Michelen M, Manoharan L, Elkheir N, Cheng V, Dagens A, Hastie C, et al. Characterising long COVID: a living systematic review. BMJ glob health 2021;6(9):e005427.
Drey M. Pfeifer K, Sieber CC, Bauer JM, The Fried frailty criteria as inclusion criteria for a randomized controlled trial: personal experience and literature review. Gerontology 2011;57(1):11-8.
Bielza R, Sanz J, Zambrana F, Arias E, Malmierca E, Portillo L, et al. Clinical characteristics, frailty, and mortality of residents with COVID-19 in nursing homes of a region of Madrid. J Am Med Dir Assoc 2021; 22(2):245-52.
Pizano-Escalante MG, Anaya-Esparza LM, Nuño K, Rodríguez-Romero JJ, Gonzalez-Torres S, López-de la Mora DA, et al. Direct and indirect effects of COVID-19 in frail elderly: interventions and recommendations. J Pers Med 2021;11(10):999.
Mendes A, Herrmann FR, Périvier S, Gold G, Graf CE, Zekry D. Delirium in older patients with COVID-19: prevalence, risk factors, and clinical relevance. J Gerontol A Biol Sci Med Sc 2021;76(8):e142-6.
Mcloughlin BC, Miles A, Webb TE, Knopp P, Eyres C, Fabbri A, et al. Functional and cognitive outcomes after COVID-19 delirium. Eur Geriatr Med 2020;11(5):857-62.
O’Hanlon S, Inouye SK. Delirium: a missing piece in the COVID-19 pandemic puzzle. Age Ageing 2020; 49(4):497-8.
Bakker ED, van de Pas SL, Zwan MD, Gillissen F, Bouwman FH, Scheltens P, et al. Steeper memory decline after COVID-19 lockdown measures. Alzheimers Res Ther 2023;15(1):1-9.
Simonetti A, Pais C, Jones M, Cipriani MC, Janiri D, Monti L, et al. Neuropsychiatric symptoms in elderly with dementia during COVID-19 pandemic: definition, treatment, and future directions. Front psychiatry 2020; 11:579842.
Numbers K, Brodaty H. The effects of the COVID-19 pandemic on people with dementia. Nat Rev Neurol 2021;17(2):69-70.
Cagnin A, Lorenzo RD, Marra C, Bonanni L, Cupidi C, Lagana V, et al. Behavioral and psychological effects of coronavirus disease-19 quarantine in patients with dementia. Front psychiatry 2020;11:578015.
Sciacqua A, Pujia R, Arturi F, Hribal ML, Montalcini T. COVID-19 and elderly: beyond the respiratory drama. Intern Emerg Med 2020;15(5):907-9.
Aguiar GB, Dourado KF, Andrade MIS, Domingos Júnior IR, Barros-Neto JA, Vasconcelos SML, et al. Frequency and factors associated with sarcopenia prediction in adult and elderly patients hospitalized for COVID-19. Exp Gerontol 2022;168:111945.
Abdelbasset WK. Stay Home: Role of physical exercise training in elderly individuals’ ability to face the covid-19 infection [Internet]. 2020 [Cited 2023 Jun 6]. Available from: https://pubmed.ncbi.nlm.nih.gov/33354578/ psychological
Lee K, Jeong GC, Yim J. Consideration of the and mental health of the elderly during COVID-19: A theoretical review. Int J Environ Res Public Health 2020;17(21):8098.
อรัญญา ตุ้ยคัมภีร์. ความ สัมพันธ์ ระหว่าง สุข ภาวะ ทาง สังคม และ ปัญหา สุขภาพ จิต ของ ผู้ สูงอายุ ใน ช่วง สถานการณ์ การ แพร่ ระบาด ของ โค วิด 19. วารสารศึกษาศาสตร์ มสธ. มหาวิทยาลัยสุโขทัยธรรมาธิราช2022;15(2):133-46.
ภาคิน โชติเวศย์ศิลป์. ความมั่นคงระหว่างประเทศภายหลังการระบาด COVID-19. วารสารนาคบุตรปริทรรศน์ 2022;14(1):132-45.
Martins Van Jaarsveld G. The effects of COVID-19 among the elderly population: a case for closing the digital divide. Front Psychiatry 2020;11:1211.