Correlation and Clinical Significance of Low Birth Weight Infant and Maternal Anemia at Surin Hospital
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Abstract
Objective: To study effect of maternal anemia with low birth weight infant and other perinatal outcomes.
Materials and Methods: A retrospective 6,171 pregnant women were studied from January 1, 2012 to December 31, 2012 at Department of Obstetrics and Gynecology, Surin Hospital, Thailand. The study group consisted of 1,336 anemic pregnant women (hematocrit less than 33% at first antenatal care) gave birth in Surin Hospital and the control group consisted of 4,835 non-anemic pregnant women (hematocrit > 33% at first ANC) gave birth in Surin Hospital. Demographic data and perinatal outcomes (included low birth weight at delivery, preterm delivery, Apgar score at 1 and 5 min, mode of delivery, and hospitalization) were collected and compared between the study and control groups. Data was analysed using descriptive statistics and presented as mean + SD and percentage. Statistical significance was using the Chi-square test and Fisher’s Exact test for differences in qualitative variables and the student t-test for differences in continuous variables. 95% confidence interval (Cl) were computed p-value less than 0.05 were considered statistically significant.
Results: The anemic pregnant women tended to be younger, lower body weight, late first antenatal care visit and have newborn large for gestational age. There was no difference between maternal anemic status and maternal non-anemic status to route of delivery (70.6%, 64.1%; p=0.0001) significantly. But there was no difference between maternal anemic status and maternal non-anemic status to low birth weight (9.4%, 11.1%; p = 0.216), birth asphyxia (3.3%, 3.7%; p = 0.540), and newborn admission to SNB & NICU (5.0%, 6.0%; p = 0.150) insignificantly.
Conclusion: There was no significant difference between anemic pregnant women and non-anemic pregnant women to route of delivery.
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References
2. Amalia L A, Drora F B, Miriam Katz C, Moshe M C, Eyal S. Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. EJOGRB. Elsevier Ireland Ltd 2005;122:182-6.
3. Bondevik GT, Lie RT, Ulstein M, Kvale G. Maternal hematological status and risk of low birth weight and preterm delivery in Nepal. Acta Obstet Gynecol Scand 2001;80:402-8.
4. Ren A, Wang J., Ye R.W., Li S., Liu J.M., Z. Li. Low first-trimester hemoglobin and low birth weight, preterm birth and small for gestational age newborns. Int J Gynecol Obstet 2007;98:124-8.
5. Henna Hamalainen, Katja Hakkarainen, Seppo Heinonen. Anaemia in the first but not in the second or third trimester is a risk factor for low birth weight. Clin Nutr 2003;22:271-5
6. Farah Wali Lone, Rahat Najam Qureshi, Faran Emanuel. Maternal anaemia and its impact on perinatal outcome. Trop Med Int Health 9. 2004;486-90.
7. Monika Malhotra, Sharma J.B., Batra S., Sharma S., Murthy N.S., Arora R. Maternal
and perinatal outcome in varying degrees of anemia. Int J Gynecol Obstet 2002;79:93-100.
8. Scanlon KS, Yip R, Schieve LA, Cogswell ME. High and low haemoglobin levels
during pregnancy: differential risks for preterm birth and SGA. Obstet Gynecol 2000;96:741-7.
9. Chumnijarakij T, Nuchprayoon T, Chiti-nand S, Onthuam Y, Quamkul N, Dusitsin
N, et al. Maternal risk factors for low birth weight newborn in Thailand. J Med Assoc Thai 1992;75:445-52.
10. Cessie S Le, Verhoeff F H, Mengistie G, Kazembe P, Broadhead R, Brabin B J. Changes in Haemoglobin levels in infants in Malawi: effect of low birth weight and fetal anaemia. Arch Dis Child Fetal Neonatal Ed 2002;86:182-7.
11. World Health Organization. Managing Complications in Pregnancy and Childbirth. Geneva: World Health Organization; 2000.
12. World Health Organization. Pregnancy, Childbirth, Postpartum and Newborn Care: A Guide for Essential Practice. Geneva: World Health Organization, 2nd Edition; 2005.
