Active Role of Pharmaceutical Care for Oncology Patients
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Abstract
Background: Medication monitoring in cancer patients receiving injectable chemotherapy drugs has shown prescribing errors and administrating errors. These caused several serious adverse drug reactions (ADR). Multidisciplinary team has been established to provide care for systemic problem solving. This study aimed to assess pharmacist role in management of therapy related problem and prevention of repeated serious therapy problems.
Methods: Prospective descriptive study was performed. Patients receiving injectable chemotherapy drugs, in Surin Hospital, during October 1st 2010 to September 30st 2012 (Fiscal year 2011 and 2012) were included. Pharmaceutical care was provided to the patients. Descriptive statistics were analyzed.
Results: There were 2,365 patients with 3,927visits. Cytotoxic drugs were prepare to 8,705 doses. Pharmaceutical care provided to cancer patients were 2,802 times, 290 drug information services, 2,802 nutrition consults and 69 reimbursement team consults. We found 1,348 drug related problems which the most problems were ADR (78.0%), medication error (9.5%), needed for additional drug therapy (3.1 %), improper dosage regimen (3.1%), improper drug selection (0.2 %), non compliance (4.7%), failed to receive medication (3.0%), drug interaction (0), duplication of medications (0) and other problems (1.3%). Side effects were the most frequent ADR (99.3%) and serious ADR were 20.4%. Drug related problems were solved 97.8% and all serious ADR could be prevented. There were 2,802 pharmacist interventions.
Conclusion: Regarding multidisciplinary team approach, pharmacist has a role in solving medication problems and preventing serious ADR. เท addition, pharmacists review the order to ensure the accepted reimbursment of therapy.
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References
2. Liekweg A, Westfeld M, Jaehde U. From oncology pharmacy to pharmaceutical care: new contributions to multidis-ciplinary cancer care. Support Care Cancer Off J Multinatl Assoc Support Care Cancer. กุมภาพันธ์ 2004;12:2:73-9.
3. โรงพยาบาลสุรินทร์ กลุ่มงานเภสัชกรรม งานผลิตยา. รายงานผู้ป่วยรับยาฉีดเคมีบำบัด โรงพยาบาลสุรินทร์ ปี 2553-2556. สุรินทร์: กลุ่มงานเภสัชกรรม โรงพยาบาลสุรินทร์ ; 2556.
4. พัชฎาพร เสาทอง. อุบัติการณ์การเกิดอาการ ไม่พึงประสงค์จากการใช้ยาฉีดเคมีบำบัดใน โรงพยาบาลสุรินทร์ : วารสารข่าวสารด้านยา และผลิตภัณฑ์สุขภาพ 2555;15:3:82-89.
5. Lihara H, Ishihara M, Matsuura K, Kurahashi S, Takahashi T, Kawaguchi Y และคณะ. Pharmacists contribute to the improved efficiency of medical practices in the outpatient cancer chemotherapy clinic. J Eval Clin Pract 2012)18:4:753-60.
6. Dominic A. Solimando Jr. American Pharmacist Association ; Drug information handbook for oncology. 7th ed. Hudson, Ohio Lexi-Comp :American Pharmaceutical Association, 2008.
7. National Comprehensive Cancer Network; NCCN Practice Guidelines in Oncology v2 2011
8. Sessions JK, Valgus J, Barbour SY, lacovelli L. Role of Oncology Clinical Pharmacists in Light of the Oncology Workforce Study. J Oncol Pract 2010;6:5:270-82.
9. Subongkot S, Srisawat S, Johns NP, Sookprasert A Outcome of Chemotherapy Counseling in Oncology Patients by Pharmacist. Isan J Pharm Sci 2010;5:1:34-45.
10. Cioffi P, Antonelli D, Belfiglio M, Melena S, Petrelli F, Grappasonni I. The impact of a pharmacist as a member of healthcare team on facilitating evidenced-based prescribing of innovative drugs in an Italian oncology department. J Oncol Pharm Pract 2012;18:2:207-12.
11. Lopez-Martin C, Siles MG, Alcaide- Garcia J, Felipe VF. Role of clinical pharmacists to prevent drug interactions in cancer outpatients: a single-centre experience. Int J Clin Pharm 2014;36:6:1251-9.
12. Delpeuch A, Leveque D, Gourieux B, Herbrecht R. Impact of Clinical Pharmacy Services in a Hematology/Oncology Inpatient Setting. Anticancer Res 2015;35:1:457-60.
13. Mancini R. Implementing a standardized pharmacist assessment and evaluating the role of a pharmacist in a multidis-ciplinary Supportive oncology clinic. J Support Oncol 2012;10:3:99-106
14. Chan A, Shih V, Chiang J, Chew L, Tay K, Quek Ru, และคณะ. Clinical pharmacy services and research for lymphoma patients at a cancer center. J Oncol Pharm Pract Off Publ Int Soc Oncol Pharm Pract 2013;19:l:24-30.
15. Tuffaha HW, Abdelhadi O, Omar SA. Clinical pharmacy services in the outpatient pediatric oncology clinics at a comprehensive cancer center. Int J Clin Pharm 2012;34:1:27-31.
16. Osama M, AI-Quteimat, AI-Badaineh. Role of oncology clinical pharmacist: a case of life-saving interventions. Int J Basic Clin Pharmacol 2013;2:5:655.
17. American Society of Health-System Pharmacists. Oncology Pharmacy Preparatory Review Course. The American College of Clinical Pharmacy and the American Society of Health-System Pharmacists ;2008.
