Comparison of Maternal Oxygen Administration and Non-administration During the Second stage of Labor on Umbilical Arterial Cord Blood Gas
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Abstract
Background: Maternal oxygen administration has been routinely used especially in an attempt to lessen fetal distress. Several studies demonstrated a beneficial outcome but some literature claimed that prolonged or high inspired oxygen during labor resulted in low blood gas status in umbilical artery. Therefore in this study aimed to confirm the effects of supplemental oxygen during the second stage of normal labor on cord blood gas values in Surin hospital.
Objectives: To compare the results of umbilical arterial cord blood gas between the group of maternal oxygen administration and non-administration during the second stage of labor in Surin hospital.
Setting: Department of obstetrics and gynecology, Surin hospital. Study design : Prospective experimental study (randomized clinical trial)
Method: 52 normal term women in the second stage of labor were randomized to receive either lOL/min oxygen by mask with bag or room air. Umbilical arterial cord blood gas was collected at delivery and the outcome was compared between the two groups.
Result: There was no difference in APGAR score at 1, 5 and 10 min. between two groups. The oxygenation group had significantly lower mean PaO2 than the control group (15.15±3.0 mmHg, 17.38±4.58mmHg, p=0.043) and had significantly greater mean PaCO2 (58.50±7.04 mmHg,53.62±8.39, p=0.028), greater mean bicarbonate (27.60±1.33 mmol/l, 26.60±2.13mmol/l, p=0.048) than the control group. There were no differences between mean pH and mean base excess. The mean time receiving oxygen was 23.81±16.58 min..
Conclusion: In a randomized, controlled, prospective trial, prolonged oxygen administration during the second stage of normal labor resulted in a deterioration of cord blood gas analysis at birth. Further prospective studies should be performed to confirm this result.
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References
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