Acute Porphyria Attack After Anesthesia : A Case Report
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Abstract
Porphyria is the group of diseases with abnormal heme metabolism. This conditions is unusual in Thai population. Patient may present with multiple organ involvement such as cutaneous manifestation, neurologic or mental symptoms or both base on each type of porphyrias. In some cases show visceral symptoms that may be misdiagnosis with acute abdominal condition. Many drugs may be trigger porphyria attack and should be concerned in treatment planning.
A 36 years old Thai man, was referred to Buriram hospital with acute abdominal pain. He also had clinical dehydration and severe tachycardia intraoperative period with no abnormal surgical condition in peritoneum. Postoperative period he had dark urine. After investigation shows positive urine spectophotometry and urine porphobilnogen is detected. His diagnosis is acute porphyria attack. In this case offered symptomatic and supportive treatment with analgesic and high glucose diets. His symptom was resolved and he had discharged from hospital in 2 week. Retrospective review shows induction with thiopental may be precipitated this attack.
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References
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