Scrub Typhus in Buriram Hospital : A Clinical Comparison Study in Scrub Typhus with Non Scrub Typhus Patients
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Abstract
Purpose: To describe and compare the clinical sign and symptom, Laboratory finding, Treatment outcome in Acute undifferentiated febrile illness (AUFI) Patients diagnosed as scrub typhus with AUFI patients diagnosed as non scrub typhus.
Design: Prospective, descriptive study using Percentile, standard deviation, Mann Whitney U - Test
Location: Medical department. Buriram Hospital Thailand.
Methods: During Sept 1st to Nov. 30th 2003, the 30 in patients who come with AUFI. The clinical sign and symptoms :Laboratory finding and were analysed and compared with these two groups. Treatment outcome were analysed in scrub typhus group.
Results: The patients were devided by IFA Technique 19 patients were scrub typhus and 11 patients were non scrub typhus group. There were no statistical different between two groups in clinical sign and symptom. The fever with chill was found more frequence in scrub typhus group (73.7%, p = 0.015) while the calf pain were found more frequence in non scrub typhus (45.5%, p = 0.032) Laboratory finding : No statistical different in complete blood count and urinalysis while bilirubin and creatine were higher in non scrub typhus group (P=0.033, p=0.034), The treatment outcome, after Doxycycline administered in scrub typhus group, the fever decrease in 78.9% of patients with in 48 hours.
Conclusion: The competency of laboratory analysis were the major constrain in diagnosing scrub typhus in provincial hospital. The AUFI patienis could lead to complication and mortality without good diagnosis and management.
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References
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