Spinal Anesthesia with Ropivacaine for Caesarean Section : A Comparison of 0.75% and 1% Solutions
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Abstract
Background: The dose-response relation for spinal ropivacaine is undetermined and there are few data available for obstetric Thai patients.
Objective: To evaluate the clinical efficacy and safety of ropivacaine when employed for spinal anesthesia in Thai patients.
Setting: Department of Anesthesiology, Surin Hospital.
Research design: Randomized trial
Subjects: One hundred and four patients who underwent cesarean delivery in Surin Hospital, from May 1, 2002 to January 31, 2003.
Methods: We compared, the characteristics of spinal anesthesia with 0.75 and 1% ropivacaine. Sensory changes assessed by pin prick and motor changes assessed by Modified Bromage Scale.
Results: Spinal ropivacaine was successful in 88.46 and 96.15 % of the 0.75 and 1 % groups. Duration of sensory and motor block, degree of motor block and time to first analgesic requirement, but not onset of anesthesia, were positively related to dose.
Conclusion: Ropivacaine is a suitable alternative agent for spinal anesthesia, in dose of 18.75 and 25 mg, was well tolerated and provided effective anesthesia for cesarean delivery in Thai patients.
Key words: Ropivacaine, Spinal anesthesia, Cesarean delivery
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References
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