Effectiveness of Benzydamine Hydrochloride Spray on Laryngeal Mask Airway in Reducing Postoperative Sore Throat after General Anesthesia : A Randomized Control Trial
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Abstract
Background: Postoperative Sore Throat (POST), the minor postoperative complication, is common after general anesthesia. However, POST affects quality of care and patient satisfaction who received general anesthesia. Multiple factors lead to POST after laryngeal mask, none the less prevention of POST is still controversy.
Objective: To study effectiveness of prescribing Benzydamine Hydrochloride Spray, topical non-steroidal anti-inflammatory drug, with Laryngeal Mask Airway (LMA) in reducing postoperative sore throat among patients who under went general anesthesia in general surgery, orthopedics and gynecologic departments.
Methods: We conducted a randomized control trial, double blind. The study population was patients who underwent a general anesthesia with LMA. Patients with intervention will be prescribed Benzydamine Hydrochloride Spray on LMA. Incidence of postoperative sore throat at the first hour and the twenty-forth hour after the surgery, hoarseness, and patient satisfaction of general anesthesia were analyzed and compared to the control group. The patient satisfaction scores will be evaluated from 0 (unsatisfied)-10 (most satisfied).
Results: Of 96 patients, twenty-six and thirteen patients developed sore throat at the first hour and the twenty-fourth hour. We detected the difference between intervention and control group. The application of Benzydamine Hydrochloride Spray on LMA was able to reduce the incidence of postoperative sore throat at the first (40.8% vs.12.8%) and the twenty-fourth hour (24.5% vs. 2.1%) after surgery with statistically significant (p-value 0.021 and 0.006, respectively). There are no significant differences in hoar seness and patient satisfaction.
Conclusion: The application of Benzydamine Hydrochloride Spray on LMA is able to reducethe incidence of postoperative sore throat at the first and the twenty-forth hour after surgery with statistical significance. However, Benzydamine Hydrochloride Spray may not reduce hoar seness and increase patient satisfaction. No further complication from Laryngeal mask airway during general anesthesia.
Keywords: Postoperative Sore Throat, Benzydamine Hydrochloride Spray
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References
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