Effect of Triamcinolone Acetonide Paste Applied Over Laryngoscope Blade on Postoperative Sore Throat
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Abstract
Background: Postoperative sore throat (POST) is the most common minor complication in general anesthesia. Incidence is 50% of patient undergoing general anesthesia and highest in tracheally intubated patient The objective was to examine whether laryngoscope blade pasted with 0.1% triamcinolone acetonide 0.5 mg reduces the incidence and severity of POST.
Methods: This study was a double-blind randomized controlled trial in elective surgical patients aged 18-60 years, ASA l-ll, duration of anesthesia 30-240 minutes. The patients were randomized into two groups; the triamcinolone group (n=58) and the sterile water-soluble gel group (n=59). Before intubation, laryngoscope blade was pasted with 0.1% triamcinolone acetonide 0.5 mg in the triamcinolone group and sterile water-soluble gel 0.5 ml the sterile water-soluble gel group. The incidence and severity of POST were evaluated for 1 hour and 24 hours after the operation.
Results: Of the 117 patients in the study, the incidence of POST was not significantly lower in the triamcinolone group compared with the sterile water-soluble gel group at 24 hrs. (31.0% vs 42.4%; p=0.203) and 1 hr. (32.8% vs 34.0%; p=0.896). The severity of POST was not significantly lower in the triamcinolone group compared with the sterile water-soluble gel.
Conclusion: The incidence and severity of POST were not statistically significant differences in the triamcinolone group compared with the sterile water soluble gel group.
Keywords: Postoperative sore throat, triamcinolone acetonide
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References
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