Predictive Factors of mortality among heart failure patients in Buri Ram Hospital Fiscal Years 2018-2020
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Abstract
Background: Heart failure is a major cause for hospitalizations and high mortality rates. Outcomes following heart failure (HF) hospitalizations are poor.
Objective: This study aimed to investigate the mortality rate of heart failure, the risk factors related to mortality of heart failure in Buri Ram Hospital.
Methods: It’s was conducted as a retrospective case control study. The sample of 2,095 heart failure patients admitted to Buri Ram Hospital between October 2018 and September 2020 were included. A total of 290 subjects were selected by systemic sampling, 1:1. Data were collected by the retrospective medical review and analyzed using by descriptive statistics Chi-square test Fisher’s exact and Multivariable logistic regression
Results: The overall Heart Failure Mortality rate was 7.2%, a Predictive Factors of mortality in patients with heart failure were significantly associated with Pneumonia (OR 2.32 95%CI 1.01-5.33 p=0.047), Cardiac arrhythmia (OR 3.83 95%CI 1.76-8.33 p=0.001), Acute respiratory failure (OR 5.79 95%CI 2.88-11.63 p<0.001), Shock (OR 16.66 95%CI 5.06-54.90 p<0.001), and serum albumin level ≤ 3.4 g/dL (OR 3.59 95%CI 1.78-7.23 p< 0.001). Presence of all five factors have a positive predictive value of 80%.
Conclusions: The finding of this study offers specific insights for care of heart failure patients. These data can assist clinical assessment of patient symptom severity to provide appropriate interventions. That is, patients with the five aforementioned co-morbidities of pneumonia, cardiac arrhythmia, acute respiratory failure, shock, and serum albumin levels ≤ 3.4 g/dL in the hospital setting can be more rapidly treated to decrease heart failure mortality outcomes.
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References
รังสฤษฎ์ กาญจนะวณิชย์, อรินทยา พรหมินธิกุล, ภูขวัญ อรุณมานะกุล, อนงค์ อมฤตโกมล. คู่มือการดูแลผู้ป่วยโรคหัวใจล้มเหลวเรื้อรังแบบบูรณาการ. พิมพ์ครั้งที่ 2. กรุงเทพฯ : คอนเซ็พท์ เมดิคัส จำกัด ; 2558.
สมาคมแพทย์โรคหัวใจแห่งประเทศไทย ในพระบรมราชูปถัมภ์. แนวทางเวชปฏิบัติเพื่อการวินิจฉัยและการดูแลรักษาผู้ป่วยภาวะหัวใจล้มเหลว พ.ศ. 2562. สมุทรปราการ : เนคสเตป ดีไซน์ ; 2562.
Moleerergpoom W, Hengrussamee K, Piyayotai D, Jintapakorn W, Sukhum P, Kunjara-Na-Ayudhya R, et al. Predictors of in-hospital mortality in acute decompensated heart failure (Thai ADHERE). J Med Assoc Thai 2013;96(2):157-64.PMID: 23936980
Luna CM, Palma I, Niederman MS, Membriani E, Giovini V, Wiemken TL, et al. The Impact of Age and Comorbidities on the Mortality of Patients of Different Age Groups Admitted with Community-acquired Pneumonia. Ann Am Thorac Soc 2016;13(9):1519-26. doi: 10.1513/AnnalsATS.201512-848OC.
Doval HC, Nul DR, Grancelli HO, Varini SD, Soifer S, Corrado G, et al. Nonsustained ventricular tachycardia in severe heart failure. Independent marker of increased mortality due to sudden death. GESICA-GEMA Investigators. Circulation 1996;94(12):3198-203. doi: 10.1161/01.cir.94.12.3198.
Pokorney SD, Al-Khatib SM, Sun JL, Schulte P, O'Connor CM, Teerlink JR, et al. Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF. Eur J Heart Fail 2018;20(3):525-32. doi: 10.1002/ejhf.1078.
Delerme S, Ray P. Acute respiratory failure in the elderly: diagnosis and prognosis. Age Ageing 2008;37(3):251-7. doi: 10.1093/ageing/afn060.
Ray P, Birolleau S, Lefort Y, Becquemin MH, Beigelman C, Isnard R, et al. Acute respiratory failure in the elderly: etiology, emergency diagnosis and prognosis. Crit Care 2006;10(3):R82. doi: 10.1186/cc4926.
Wuerz RC, Meador SA. Effects of prehospital medications on mortality and length of stay in congestive heart failure. Ann Emerg Med 1992;21(6):669-74. doi: 10.1016/s0196-0644(05)82777-5.
Zannad F, Mebazaa A, Juillière Y, Cohen-Solal A, Guize L, Alla F, et al. Clinical profile, contemporary management and one-year mortality in patients with severe acute heart failure syndromes: The EFICA study. Eur J Heart Fail 2006;8(7):697-705. doi: 10.1016/j.ejheart.2006.01.001.
Oh DH, Kim MH, Jeong WY, Kim YC, Kim EJ, Song JE, et al. Risk factors for mortality in patients with low lactate level and septic shock. J Microbiol Immunol Infect 2019;52(3):418-25. doi: 10.1016/j.jmii.2017.08.009.
Uthamalingam S, Kandala J, Daley M, Patvardhan E, Capodilupo R, Moore SA, et al. Serum albumin and mortality in acutely decompensated heart failure. Am Heart J 2010;160(6):1149-55. doi: 10.1016/j.ahj.2010.09.004.
Ancion A, Allepaerts S, Oury C, Gori AS, Piérard LA, Lancellotti P. Serum albumin level and hospital mortality in acute non-ischemic heart failure. ESC Heart Fail 2017;4(2):138-45. doi: 10.1002/ehf2.12128.
จิตติพร ภู่รัตนมาลย์. ปัจจัยทำนายการรอดชีวิตของกลุ่มผู้ป่วยโรคหัวใจล้มเหลวในหอผู้ป่วยอายุรกรรม ของโรงพยาบาลมหาราชนครศรีธรรมราช. วารสารวิชาการแพทย์ เขต 11 2560;31(3):483-93.