Efficacy of Trabeculectomy on IOP in Phakic Versus Pseudophakic among POAG Patients at Debaratana Nakhon Ratchasima Hospital

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wisakorn wongwijitsook

Abstract

Background: Glaucoma is a degenerative optic nerve disease, the second leading cause of vision loss globally. The treatment aims to lowering IOP for stabilize the glaucoma and prevent further visual field loss.
Objective: This study compare efficacy of trabeculectomy on IOP between phakic and pseudophakic status among POAG patients.
Methods: It's a retrospective descriptive study using medical records and case record form. Assessment occurs at 1 week, 1 month, 3 month, and 6 months.The post surgery sample is primary open angle glaucoma patients who had surgery at Debaratana Nakhon Ratchasima Hospital (July 2021 to January 2023). The analysis employed Repeated measurement analysis assessed variance and Generalized Estimating Equation with 95% confidence.
Results: The study found that among patients with primary open angle glaucoma, 13 had phakia (52.0%), and 12 had pseudophakia (48.0%). No significant difference was detected when comparing changes in intraocular pressure after 6 months of surgery between phakic and pseudophakic patients. However, at least one pair had significant differences in postoperative visual acuity and intraocular pressure levels (p<0.001). Additional procedures after surgery also differed significantly in at least one pair (p=0.013).
Conclusion: After trabeculectomy for 6 months, IOP in phakic and pseudophakic among POAG patients were decreased. However, no statistically significant differences were found between the two groups.

Article Details

How to Cite
wongwijitsook, wisakorn. (2023). Efficacy of Trabeculectomy on IOP in Phakic Versus Pseudophakic among POAG Patients at Debaratana Nakhon Ratchasima Hospital. MEDICAL JOURNAL OF SISAKET SURIN BURIRAM HOSPITALS, 38(3), 869–878. retrieved from https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/265140
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Original Articles

References

Halpern DL, Grosskreutz CL. Glaucomatous optic neuropathy: mechanisms of disease. Ophthalmol Clin North Am 2002;15(1):61-8. doi: 10.1016/s0896-1549(01)00012-8.

Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 2014;121(11):2081-90. doi: 10.1016/j.ophtha.2014.05.013.

Iwase A, Suzuki Y, Araie M, Yamamoto T, Abe H, Shirato S, et al. The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology 2004;111(9):1641-8. doi: 10.1016/j.ophtha.2004.03.029.

Kim M, Kim TW, Park KH, Kim JM. Risk factors for primary open-angle glaucoma in South Korea: the Namil study. Jpn J Ophthalmol 2012;56(4):324-9. doi: 10.1007/s10384-012-0153-4.

No authors listed. The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS Investigators. Am J Ophthalmol 2000;130(4):429-40. doi: 10.1016/s0002-9394(00)00538-9.

Broadway DC, Grierson I, Hitchings RA. Local effects of previous conjunctival incisional surgery and the subsequent outcome of filtration surgery. Am J Ophthalmol 1998;125(6):805-18. doi: 10.1016/s0002-9394(98)00045-2.

Supawavej C, Nouri-Mahdavi K, Law SK, Caprioli J. Comparison of results of initial trabeculectomy with mitomycin C after prior clear-corneal phacoemulsification to outcomes in phakic eyes. J Glaucoma 2013;22(1):52-9. doi: 10.1097/IJG.0b013e31821e8607.

Khairallah M, Kahloun R, Flaxman SR, Jonas JB, Keeffe J, Leasher J, et al. Prevalence and causes of vision loss in North Africa and the Middle East: 1990-2010. Br J Ophthalmol 2014;98(5):605-11. doi: 10.1136/bjophthalmol-2013-304068.

Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmo. 2006;90(3):262-7. doi: 10.1136/bjo.2005.081224.

Elgazar AF. Outcome of Trabeculectomy in Phakic and Pseudophakic Eyes with Open Angle Glaucoma after Phacoemulsification: A retrospective Comparative Study. IJMA 2022;4 (2):2124-8. DOI: 10.21608/ijma.2022.221048

Bigger JF, Becker B. Cataracts and primary open-angle glaucoma: the effect of uncomplicated cataract extraction on glaucoma control. Trans Am Acad Ophthalmol Otolaryngol 1971;75(2):260-72.PMID: 4933971

Friedman DS, Jampel HD, Lubomski LH, Kempen JH, Quigley H, Congdon N, et al. Surgical strategies for coexisting glaucoma and cataract: an evidence-based update. Ophthalmology 2002;109(10):1902-13. doi: 10.1016/s0161-6420(02)01267-8.

Matsumura M, Mizoguchi T, Kuroda S, Terauchi H, Nagata M. [Intraocular pressure decrease after phacoemulsification-aspiration+ intraocular lens implantation in primary open angle glaucoma eyes]. [Article in Japanese]. Nippon Ganka Gakkai Zasshi 1996;100(11):885-9. PMID: 8953892

Poley BJ, Lindstrom RL, Samuelson TW, Schulze R Jr. Intraocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes: evaluation of a causal relationship between the natural lens and open-angle glaucoma. J Cataract Refract Surg 2009;35(11):1946-55. doi: 10.1016/j.jcrs.2009.05.061.

Hayashi K, Hayashi H, Nakao F, Hayashi F. Changes in anterior chamber angle width and depth after intraocular lens implantation in eyes with glaucoma. Ophthalmology 2000;107(4):698-703. doi: 10.1016/s0161-6420(00)00007-5.

Torres-Costa S, Melo AB, Estrela-Silva S, Falcão-Reis F, Barbosa-Breda J. Effect of Prior Phacoemulsification Surgery in Trabeculectomy Surgery Outcomes. Clin Ophthalmol 2022;16:357-67. doi: 10.2147/OPTH.S348364.

Dada T, Bhartiya S, Begum Baig N. Cataract Surgery in Eyes with Previous Glaucoma Surgery: Pearls and Pitfalls. J Curr Glaucoma Pract 2013;7(3):99-105. doi: 10.5005/jp-journals-10008-1145.

Takihara Y, Inatani M, Ogata-Iwao M, Kawai M, Inoue T, Iwao K, et al. Trabeculectomy for open-angle glaucoma in phakic eyes vs in pseudophakic eyes after phacoemulsification: a prospective clinical cohort study. JAMA Ophthalmol 2014;132(1):69-76. doi: 10.1001/jamaophthalmol.2013.5605.