Histological Differentiation Study of Squamous Cell Carcinoma of the Lip at Buri Ram Hospital

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Published: Dec 29, 2023
Keywords:
Squamous cell carcinoma Tumor differentiation Lip cancer

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Pucharaporn Jiengjariyanont
Department of Pathology, Buri Ram Hospital, Buri Ram, Thailand, 31000

Abstract

Background: Lip cancers constitute about 30% of all oral cavity cancers. Squamous cell carcinoma accounts for 90% of all malignant tumors of the lip. This research is pathological study of patients who underwent the surgery of squamous cell carcinoma of the lip at Buri Ram hospital. Based on tumor differentiation, the prevalence of high-grade tumor data is important for surgeon when choosing treatment protocol and making the prognosis.
Objective: To determine the prevalence of high-grade tumor differentiation of squamous cell carcinoma of lip at Buri Ram hospital.
Methods: Descriptive study, medical records and pathological reports of squamous cell carcinoma patients from 1st January 2017 to 18th July 2023 were reviewed. Data collection and analysis of age, sex, location of tumor, size of tumor, tumor differentiation, angiolymphatic invasion (ALI) status and perineural invasion (PNI) status were performed. All data were divided into three groups according to tumor differentiation. Data were analyzed using counting number, percentage, mean and standard deviation.
Results: A total of 99 of the 111 patients (89.2%) showed well differentiated squamous cell carcinoma of lip, 11 patients (9.9%) showed moderately differentiated tumors and 1 patient (0.9%) showed poorly differentiated tumors. The prevalence of ALI was 3.6% (4 from 111 patients). There were 3 patients (3.6%) in well differentiated group and 1 patient (9.1%) in moderately differentiated group. PNI was found in 1 case (100%) in poorly differentiated group, 2 of 11 patients (18.2%) in moderately differentiated group and 1 of 99 patients (1%) in well differentiated group.
Conclusion: The prevalence of high-grade tumor differentiation of squamous cell carcinoma of the lip at Buri Ram hospital is 0.9%.

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How to Cite
Jiengjariyanont, P. (2023). Histological Differentiation Study of Squamous Cell Carcinoma of the Lip at Buri Ram Hospital. MEDICAL JOURNAL OF SISAKET SURIN BURIRAM HOSPITALS, 38(3), 677–687. retrieved from https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/266741
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Vol. 38 No. 3 (2023): September - December 2023
Section
Original Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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