Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature

Sakanus Vijintanawan; Kumar K C; Anchisa Aittiwarapoj; Natthamet Wongsirichat

doi:10.33192/Smj.2019.63

Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature

Authors

Sakanus Vijintanawan Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400 http://orcid.org/0000-0001-9846-8530
Kumar K C Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400 https://orcid.org/0000-0001-9620-7388
Anchisa Aittiwarapoj Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400 http://orcid.org/0000-0002-3410-4604
Natthamet Wongsirichat Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400, and Consultant of International College of Dentistry Committee, Walailuk University International College of Dentistry, Bangkok 10400 http://orcid.org/0000-0003-3005-2680

DOI:

https://doi.org/10.33192/Smj.2019.63

Keywords:

Central odontogenic fibroma; central giant cell granuloma; hybrid

Abstract

The combination of central odontogenic fibroma and central giant cell granuloma is extremely rare and has been reported in only 46 cases worldwide in previous articles. The lesion is called a hybrid central odontogenic fibroma with central giant cell granuloma like lesion (HCOF-CGCG) due to a histopathological characteristics of multinucleated giant cell and odontogenic epithelium in fibro-cellular background. We report a case of HCOF-CGCG in a 27-year old Thai male patient who was identified as the first case in Thailand. Radiographic examination showed a well-defined radiolucency lesion at posterior mandibular area. Enucleation and curettage were done and microscopic study revealed a fibro-cellular proliferating tissue containing numerous strands, cord of odontogenic epithelium, and numerous multinucleated giant cells. This report also included a literature review of the previous 45 cases.

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Published

20-09-2019

How to Cite

Vijintanawan, S., C, K. K., Aittiwarapoj, A., & Wongsirichat, N. (2019). Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature. Siriraj Medical Journal, 71(5), 426–431. https://doi.org/10.33192/Smj.2019.63

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Issue

Vol. 71 No. 5 (2019): September-October

Section

Case Report

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