Clinical Features and Factors Associated with Mortality of Naïve Pyogenic Arthritis Patients in Surin Hospital

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Published: Aug 28, 2021
Keywords:
pyogenic arthritis clinical feature associated factors mortality death

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Pinyok Srisansanee
Department of Medicine, Surin Hospitol, Surin, Thailand, 32000

Abstract

Background: Pyogenic arthritis is a serious and potentially life-threatening condition which requiresearly diagnosis and prompt treatment. The more we know about clinical presentations and the mortality predictors, the better we can manage thease cases to reduce the incidence of joint disability and death.
Objective: To determine clinical features and outcomes of naïve pyogenic arthritis patients and influencing factors predicted mortality.
Study design: Retrospective descriptive study
Methods: The medical records of naïve pyogenic arthritis patients admitted to Surin hospital during the period of January 1, 2014 to December 31, 2020 were reviewed. Pyogenic arthritis was diagnosed by identified or isolated the pathogen in a synovial fluid gram stain and/or culture.
Results: A total of 159 patients were studied with mean (SD) age of 59.0(14.0) years. The majority of cases (74.7%) had underlying disease. The most common affected joint was knee joint (71.7%). Two thirds of the patients had co-infection in other systems at presentation (66.7%). The top three most common causative rganisms were Streptococcus agalactiae, Staphylococcus aureus and Burkholderia pseudomallei (23.3%, 17.0% and 16.4%, respectively). Underwent surgical drainage was 86.2%. Complications were found in 67.3% of them and the overall mortality rate was 19.5%. A multivariate logistic regression analysis showed that age (OR1.04;95%CI1.00-1.08,p=0.049), diabetes mellitus (OR 3.42;95%CI1.16-10.07,p=0.026),eGFR at presentation below than 30 ml/min/1.73m2 (OR5.48;95%CI1.80-16.73,p=0.003), found distant site of infection at the beginning (OR24.33;95%CI2.56-231.24,p=0.005), receiving conservative treatment (OR5.78;95%CI1.48-22.60, p=0.012) and occurring complications (OR21.79;95%CI1.29-369.07,p=0.033) were significant associated with mortality.
Conclusion: The mortality of patients with pyogenic arthritis in Surin hospital was relatively high. Diabetes mellitus, renal impairment and had other system co-infections since the time presentation were indicated poor prognosis. Surgical drainage improved outcome of treatment and reduced the mortality rate.
Keywords: pyogenic arthritis, clinical features, associated factors, mortality, death

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How to Cite
Srisansanee, P. . . (2021). Clinical Features and Factors Associated with Mortality of Naïve Pyogenic Arthritis Patients in Surin Hospital. MEDICAL JOURNAL OF SISAKET SURIN BURIRAM HOSPITALS, 36(2), 465–473. retrieved from https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/252943
Issue
Vol. 36 No. 2 (2021): May - August 2021
Section
Original Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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