Risk Factors of Pneumothorax in CT-guided Transthoracic Coaxial Needle Biopsy of Thoracic Lesions
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Abstract
Background: CT-guided transthoracic coaxial needle biopsy of thoracic lesions is a minimal invasive method and suitable for lesion at peripheral location. The common complication of transthoracic needle biopsy is pneumothorax.
Objective: The objective of the study is to access the risk factor of pneumothorax in patients who underwent CT guided transthoracic biopsy using semi-automated coaxial needle.
Methods: This study is an etiognostic study with retrospective design. The data of patients who underwent CT-guided transthoracic biopsy in Maharat Nakhonratchasima hospital during October 2012 to September 2020 is collected. Baseline characteristic is summarized using descriptive statistics. The risk factor variable is evaluated using multivariate analysis.
Result: Total 270 patients who underwent CT-guided transthoracic biopsy, 160 patients were male (59.3%). The patients who had age more than 65 years were 131(48%). Underlying lung disease was found in 32 patients(11.9%). Pneumothorax was occurred in 40 patients (14.8%). Risk factors related with pneumothorax were location of the lesion and number of pleural pass. The lesion located at lower lung has greater risk of pneumothorax than the lesion at upper lung (odd ratio 3.16; 95%CI1.36-7.3, p<0.05). The number of pleural pass more than 1 layer has greater risk of pneumothorax (odd ratio 13.72;95%CI 3.08-61.12, p<0.05).
Conclusion: Pneumothorax is not uncommon complication after CT-guided transthoracic coaxial needle biopsy of lung lesions. The knowledge will guide the interventionists to prompt and prepare for the patients who may have risk of the complication.
Keywords: CT-guided transthoracic coaxial needle biopsy, Pneumothorax
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